Is BAC Transgenesis Obsolete? State of the Art in the Era of Designer Nucleases

DNA constructs based on bacterial artificial chromosomes (BACs) are frequently used to generate transgenic animals as they reduce the influence of position effects and allow predictable expression patterns for genes whose regulatory sequences are not fully identified. Despite these advantages BAC tr...

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Detalles Bibliográficos
Autores principales: Beil, J., Fairbairn, L., Pelczar, P., Buch, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413995/
https://www.ncbi.nlm.nih.gov/pubmed/22899885
http://dx.doi.org/10.1155/2012/308414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413995/
https://www.ncbi.nlm.nih.gov/pubmed/22899885
http://dx.doi.org/10.1155/2012/308414

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