Functional coating of liposomes using a folate– polymer conjugate to target folate receptors

Folate-polymer-coated liposomes were developed for targeted chemotherapy using doxorubicin (DXR) as a model drug. Folate-poly(L-lysine) (F–PLL) conjugates with a folate modification degree of 16.7 mol% on epsilon amino groups of PLL were synthesized. DXR-loaded anionic liposomes were coated with F–P...

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Detalles Bibliográficos
Autores principales: Watanabe, Kazuo, Kaneko, Makoto, Maitani, Yoshie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414201/
https://www.ncbi.nlm.nih.gov/pubmed/22888227
http://dx.doi.org/10.2147/IJN.S32853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414201/
https://www.ncbi.nlm.nih.gov/pubmed/22888227
http://dx.doi.org/10.2147/IJN.S32853

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