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A comparative study of three ternary complexes prepared in different mixing orders of siRNA/redox-responsive hyperbranched poly (amido amine)/hyaluronic acid

In this study, a novel redox-responsive hyperbranched poly(amido amine) (named PCD) was synthesized and used as a cationic polymer to form a ternary complex with small interfering RNA (siRNA) and hyaluronic acid (HA) for siRNA delivery. Here, it is hypothesized that different mixing orders result in...

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Detalles Bibliográficos
Autores principales: Chen, Cheng-Jun, Zhao, Zhi-Xia, Wang, Jian-Cheng, Zhao, En-Yu, Gao, Ling-Yan, Zhou, Shu-Feng, Liu, Xiao-Yan, Lu, Wan-Liang, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414221/
https://www.ncbi.nlm.nih.gov/pubmed/22888238
http://dx.doi.org/10.2147/IJN.S32676