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Shigatoxin-associated hemolytic uremic syndrome: current molecular mechanisms and future therapies
Hemolytic uremic syndrome is the leading cause of acute kidney injury in childhood. Ninety percent of cases are secondary to gastrointestinal infection with shigatoxin-producing bacteria. In this review, we discuss the molecular mechanisms of shigatoxin leading to hemolytic uremic syndrome and the e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414372/ https://www.ncbi.nlm.nih.gov/pubmed/22888220 http://dx.doi.org/10.2147/DDDT.S25757 |