Cargando…
Srf: A key factor controlling skeletal muscle hypertrophy by enhancing the recruitment of muscle stem cells
Adult skeletal muscles adapt their fiber size to workload. We show that serum response factor (Srf) is required for satellite cell-mediated hypertrophic muscle growth. Deletion of Srf from myofibers, and not satellite cells, blunts overload-induced hypertrophy, and impairs satellite cell proliferati...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414385/ https://www.ncbi.nlm.nih.gov/pubmed/22880147 http://dx.doi.org/10.4161/bioa.20699 |