Cargando…

Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis

Oral exposure to high concentrations of hexavalent chromium [Cr(VI)] induces intestinal redox changes, villus cytotoxicity, crypt hyperplasia, and intestinal tumors in mice. To assess the effects of Cr(VI) in a cell model relevant to the intestine, undifferentiated (proliferating) and differentiated...

Descripción completa

Detalles Bibliográficos
Autores principales: Thompson, Chad M., Fedorov, Yuriy, Brown, Daniel D., Suh, Mina, Proctor, Deborah M., Kuriakose, Liz, Haws, Laurie C., Harris, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414448/
https://www.ncbi.nlm.nih.gov/pubmed/22905163
http://dx.doi.org/10.1371/journal.pone.0042720