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Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis
Oral exposure to high concentrations of hexavalent chromium [Cr(VI)] induces intestinal redox changes, villus cytotoxicity, crypt hyperplasia, and intestinal tumors in mice. To assess the effects of Cr(VI) in a cell model relevant to the intestine, undifferentiated (proliferating) and differentiated...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414448/ https://www.ncbi.nlm.nih.gov/pubmed/22905163 http://dx.doi.org/10.1371/journal.pone.0042720 |