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Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis

Oral exposure to high concentrations of hexavalent chromium [Cr(VI)] induces intestinal redox changes, villus cytotoxicity, crypt hyperplasia, and intestinal tumors in mice. To assess the effects of Cr(VI) in a cell model relevant to the intestine, undifferentiated (proliferating) and differentiated...

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Detalles Bibliográficos
Autores principales:	Thompson, Chad M., Fedorov, Yuriy, Brown, Daniel D., Suh, Mina, Proctor, Deborah M., Kuriakose, Liz, Haws, Laurie C., Harris, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414448/ https://www.ncbi.nlm.nih.gov/pubmed/22905163 http://dx.doi.org/10.1371/journal.pone.0042720

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