The MUC1 Extracellular Domain Subunit Is Found in Nuclear Speckles and Associates with Spliceosomes

MUC1 is a large transmembrane glycoprotein and oncogene expressed by epithelial cells and overexpressed and underglycosylated in cancer cells. The MUC1 cytoplasmic subunit (MUC1-C) can translocate to the nucleus and regulate gene expression. It is frequently assumed that the MUC1 extracellular subun...

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Detalles Bibliográficos
Autores principales: Kumar, Priyadarsina, Lindberg, Louise, Thirkill, Twanda L., Ji, Jennifer W., Martsching, Lindsay, Douglas, Gordon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414450/
https://www.ncbi.nlm.nih.gov/pubmed/22905162
http://dx.doi.org/10.1371/journal.pone.0042712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414450/
https://www.ncbi.nlm.nih.gov/pubmed/22905162
http://dx.doi.org/10.1371/journal.pone.0042712

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