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The MUC1 Extracellular Domain Subunit Is Found in Nuclear Speckles and Associates with Spliceosomes
MUC1 is a large transmembrane glycoprotein and oncogene expressed by epithelial cells and overexpressed and underglycosylated in cancer cells. The MUC1 cytoplasmic subunit (MUC1-C) can translocate to the nucleus and regulate gene expression. It is frequently assumed that the MUC1 extracellular subun...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414450/ https://www.ncbi.nlm.nih.gov/pubmed/22905162 http://dx.doi.org/10.1371/journal.pone.0042712 |