Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening

Yeast RNA polymerase (Pol) II general factor TFIIE and the TFIIH subunit Ssl2/XPB function in transition of the preinitiation complex (PIC) to the open complex. We find that the three TFIIE winged helix (WH) domains form a heterodimer, with the Tfa1/TFIIEα WH binding the Pol II clamp and the Tfa2/TF...

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Detalles Bibliográficos
Autores principales: Grünberg, Sebastian, Warfield, Linda, Hahn, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414687/
https://www.ncbi.nlm.nih.gov/pubmed/22751016
http://dx.doi.org/10.1038/nsmb.2334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414687/
https://www.ncbi.nlm.nih.gov/pubmed/22751016
http://dx.doi.org/10.1038/nsmb.2334

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