5-Formyl- and 5-carboxyl-cytosine reduce the rate and substrate specificity of RNA polymerase II transcription

While the roles of 5-methyl-cytosine and 5-hydroxymethyl-cytosine in epigenetic regulation of gene expression are well-established, the functional effects of 5-formyl-cytosine and 5-carboxyl-cytosine in the genome on transcription are not clear. Here we report the first systematic study of the effec...

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Detalles Bibliográficos
Autores principales: Kellinger, Matthew W., Song, Chun-Xiao, Chong, Jenny, Lu, Xing-Yu, He, Chuan, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414690/
https://www.ncbi.nlm.nih.gov/pubmed/22820989
http://dx.doi.org/10.1038/nsmb.2346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414690/
https://www.ncbi.nlm.nih.gov/pubmed/22820989
http://dx.doi.org/10.1038/nsmb.2346

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