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Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling
The AKT family of serine threonine kinases is of critical importance with regard to growth factor signaling, cell proliferation, survival and oncogenesis. Engagement of signaling receptors induces the lipid kinase, phosphatidylinositol 3-kinase (PI3K), which enables the activation of AKT. Responsive...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414727/ https://www.ncbi.nlm.nih.gov/pubmed/22680924 http://dx.doi.org/10.2174/092986712801661130 |