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Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia

BACKGROUND: Estradiol has been shown to exert neuroprotective effects in several neurodegenerative conditions, including cerebral ischemia. The presence of this hormone prior to ischemia attenuates the damage associated with such events in a rodent model (middle cerebral artery occlusion (MCAO)), al...

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Detalles Bibliográficos
Autores principales: Pérez-Álvarez, Maria Jose, Maza, Maria del Carmen, Anton, Marta, Ordoñez, Lara, Wandosell, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414748/
https://www.ncbi.nlm.nih.gov/pubmed/22747981
http://dx.doi.org/10.1186/1742-2094-9-157