Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion

BACKGROUND: Membrane-anchored heparin-binding epidermal growth factor-like growth factor (proHB-EGF) yields soluble HB-EGF, which is an epidermal growth factor receptor (EGFR) ligand, and a carboxy-terminal fragment of HB-EGF (HB-EGF-CTF) after ectodomain shedding. We previously reported that HB-EGF...

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Detalles Bibliográficos
Autores principales: Shimura, Takaya, Yoshida, Michihiro, Fukuda, Shinji, Ebi, Masahide, Hirata, Yoshikazu, Mizoshita, Tsutomu, Tanida, Satoshi, Kataoka, Hiromi, Kamiya, Takeshi, Higashiyama, Shigeki, Joh, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414754/
https://www.ncbi.nlm.nih.gov/pubmed/22646534
http://dx.doi.org/10.1186/1471-2407-12-205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414754/
https://www.ncbi.nlm.nih.gov/pubmed/22646534
http://dx.doi.org/10.1186/1471-2407-12-205

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