Inhibition of Neurotoxic Secretory Phospholipases A(2) Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth

Secretory phospholipases A(2) (sPLA(2)) exert proinflammatory actions through lipid mediators. These enzymes have been found to be elevated in many inflammatory disorders such as rheumatoid arthritis, sepsis, and atherosclerosis. The aim of this study was to evaluate the effect of harpalycin 2 (Har2...

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Detalles Bibliográficos
Autores principales: Ximenes, Rafael M., Rabello, Marcelo M., Araújo, Renata M., Silveira, Edilberto R., Fagundes, Fábio H. R., Diz-Filho, Eduardo B. S., Buzzo, Simone C., Soares, Veronica C. G., Toyama, Daniela de O., Gaeta, Henrique H., Hernandes, Marcelo Z., Monteiro, Helena S. A., Toyama, Marcos H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415135/
https://www.ncbi.nlm.nih.gov/pubmed/22899963
http://dx.doi.org/10.1155/2012/987517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415135/
https://www.ncbi.nlm.nih.gov/pubmed/22899963
http://dx.doi.org/10.1155/2012/987517

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