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Tracking genome engineering outcome at individual DNA breakpoints

Site-specific genome engineering technologies are increasingly important tools in the post-genomic era, where biotechnological objectives often require organisms with precisely modified genomes. Rare-cutting endonucleases, through their capacity to create a targeted DNA strand break, are one of the...

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Detalles Bibliográficos
Autores principales: Certo, Michael T., Ryu, Byoung Y., Annis, James E., Garibov, Mikhail, Jarjour, Jordan V., Rawlings, David J., Scharenberg, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415300/
https://www.ncbi.nlm.nih.gov/pubmed/21743461
http://dx.doi.org/10.1038/nmeth.1648