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Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes

Dietary restriction (DR), limiting nutrient intake from diet without causing malnutrition, delays the aging process and extends lifespan in multiple organisms. The conserved life-extending effect of DR suggests the involvement of fundamental mechanisms, although these remain a subject of debate. To...

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Detalles Bibliográficos
Autores principales: Wuttke, Daniel, Connor, Richard, Vora, Chintan, Craig, Thomas, Li, Yang, Wood, Shona, Vasieva, Olga, Shmookler Reis, Robert, Tang, Fusheng, de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415404/
https://www.ncbi.nlm.nih.gov/pubmed/22912585
http://dx.doi.org/10.1371/journal.pgen.1002834