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Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes
Dietary restriction (DR), limiting nutrient intake from diet without causing malnutrition, delays the aging process and extends lifespan in multiple organisms. The conserved life-extending effect of DR suggests the involvement of fundamental mechanisms, although these remain a subject of debate. To...
Autores principales: | Wuttke, Daniel, Connor, Richard, Vora, Chintan, Craig, Thomas, Li, Yang, Wood, Shona, Vasieva, Olga, Shmookler Reis, Robert, Tang, Fusheng, de Magalhães, João Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415404/ https://www.ncbi.nlm.nih.gov/pubmed/22912585 http://dx.doi.org/10.1371/journal.pgen.1002834 |
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