APP Knockout Mice Experience Acute Mortality as the Result of Ischemia

The incidence of Alzheimer’s disease increases in people who have had an ischemic episode. Furthermore, APP expression is increased following ischemic or hypoxic conditions, as is the production of the Aβ peptide. To address the question of why APP and Aβ are increased in hypoxic and ischemic condit...

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Detalles Bibliográficos
Autores principales: Koike, Maya A., Lin, Alexander J., Pham, Jonathan, Nguyen, Elaine, Yeh, James J., Rahimian, Rombod, Tromberg, Bruce J., Choi, Bernard, Green, Kim N., LaFerla, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415410/
https://www.ncbi.nlm.nih.gov/pubmed/22912719
http://dx.doi.org/10.1371/journal.pone.0042665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415410/
https://www.ncbi.nlm.nih.gov/pubmed/22912719
http://dx.doi.org/10.1371/journal.pone.0042665

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