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Intrinsic Disorder in the Human Spliceosomal Proteome

The spliceosome is a molecular machine that performs the excision of introns from eukaryotic pre-mRNAs. This macromolecular complex comprises in human cells five RNAs and over one hundred proteins. In recent years, many spliceosomal proteins have been found to exhibit intrinsic disorder, that is to...

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Detalles Bibliográficos
Autores principales: Korneta, Iga, Bujnicki, Janusz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415423/
https://www.ncbi.nlm.nih.gov/pubmed/22912569
http://dx.doi.org/10.1371/journal.pcbi.1002641