Cargando…

Stress-Inducible Caspase Substrate TRB3 Promotes Nuclear Translocation of Procaspase-3

Pseudokinase TRB3 is a stress-inducible nuclear protein, which has recently been shown to be involved in ER stress-induced apoptosis. However, it remains unclear how TRB3 contributes to the process. We recently demonstrated that TRB3 was cleaved by caspase-3 (CASP3) in vitro and also in apoptosis-in...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimizu, Kouhei, Takahama, Shoukichi, Endo, Yaeta, Sawasaki, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415431/
https://www.ncbi.nlm.nih.gov/pubmed/22912727
http://dx.doi.org/10.1371/journal.pone.0042721