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Mutations in a P-Type ATPase Gene Cause Axonal Degeneration

Neuronal loss and axonal degeneration are important pathological features of many neurodegenerative diseases. The molecular mechanisms underlying the majority of axonal degeneration conditions remain unknown. To better understand axonal degeneration, we studied a mouse mutant wabbler-lethal (wl). Wa...

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Detalles Bibliográficos
Autores principales: Zhu, Xianjun, Libby, Richard T., de Vries, Wilhelmine N., Smith, Richard S., Wright, Dana L., Bronson, Roderick T., Seburn, Kevin L., John, Simon W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415440/
https://www.ncbi.nlm.nih.gov/pubmed/22912588
http://dx.doi.org/10.1371/journal.pgen.1002853