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HAL-2 Promotes Homologous Pairing during Caenorhabditis elegans Meiosis by Antagonizing Inhibitory Effects of Synaptonemal Complex Precursors

During meiosis, chromosomes align with their homologous pairing partners and stabilize this alignment through assembly of the synaptonemal complex (SC). Since the SC assembles cooperatively yet is indifferent to homology, pairing and SC assembly must be tightly coordinated. We identify HAL-2 as a ke...

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Detalles Bibliográficos
Autores principales: Zhang, Weibin, Miley, Natasha, Zastrow, Michael S., MacQueen, Amy J., Sato, Aya, Nabeshima, Kentaro, Martinez-Perez, Enrique, Mlynarczyk-Evans, Susanna, Carlton, Peter M., Villeneuve, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415444/
https://www.ncbi.nlm.nih.gov/pubmed/22912597
http://dx.doi.org/10.1371/journal.pgen.1002880