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Transposon-mediated Chromosomal Integration of Transgenes in the Parasitic Nematode Strongyloides ratti and Establishment of Stable Transgenic Lines

Genetic transformation is a potential tool for analyzing gene function and thereby identifying new drug and vaccine targets in parasitic nematodes, which adversely affect more than one billion people. We have previously developed a robust system for transgenesis in Strongyloides spp. using gonadal m...

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Detalles Bibliográficos
Autores principales: Shao, Hongguang, Li, Xinshe, Nolan, Thomas J., Massey, Holman C., Pearce, Edward J., Lok, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415448/
https://www.ncbi.nlm.nih.gov/pubmed/22912584
http://dx.doi.org/10.1371/journal.ppat.1002871