Lymphotoxin, but Not TNF, Is Required for Prion Invasion of Lymph Nodes
Neuroinvasion and subsequent destruction of the central nervous system by prions are typically preceded by a colonization phase in lymphoid organs. An important compartment harboring prions in lymphoid tissue is the follicular dendritic cell (FDC), which requires both tumor necrosis factor receptor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415451/ https://www.ncbi.nlm.nih.gov/pubmed/22912582 http://dx.doi.org/10.1371/journal.ppat.1002867 |