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The Drosophila Mi-2 Chromatin-Remodeling Factor Regulates Higher-Order Chromatin Structure and Cohesin Dynamics In Vivo

dMi-2 is a highly conserved ATP-dependent chromatin-remodeling factor that regulates transcription and cell fates by altering the structure or positioning of nucleosomes. Here we report an unanticipated role for dMi-2 in the regulation of higher-order chromatin structure in Drosophila. Loss of dMi-2...

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Detalles Bibliográficos
Autores principales: Fasulo, Barbara, Deuring, Renate, Murawska, Magdalena, Gause, Maria, Dorighi, Kristel M., Schaaf, Cheri A., Dorsett, Dale, Brehm, Alexander, Tamkun, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415455/
https://www.ncbi.nlm.nih.gov/pubmed/22912596
http://dx.doi.org/10.1371/journal.pgen.1002878