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The gut microbiota regulates bone mass in mice

The gut microbiota modulates host metabolism and development of immune status. Here we show that the gut microbiota is also a major regulator of bone mass in mice. Germ-free (GF) mice exhibit increased bone mass associated with reduced number of osteoclasts per bone surface compared with conventiona...

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Detalles Bibliográficos
Autores principales: Sjögren, Klara, Engdahl, Cecilia, Henning, Petra, Lerner, Ulf H, Tremaroli, Valentina, Lagerquist, Marie K, Bäckhed, Fredrik, Ohlsson, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415623/
https://www.ncbi.nlm.nih.gov/pubmed/22407806
http://dx.doi.org/10.1002/jbmr.1588