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Notch receptor–ligand binding and activation: Insights from molecular studies

The Notch receptor is part of a core signalling pathway which is highly conserved in all metazoan species. It is required for various cell fate decisions at multiple stages of development and in the adult organism, with dysregulation of the pathway associated with genetic and acquired diseases inclu...

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Detalles Bibliográficos
Autores principales: Chillakuri, Chandramouli R., Sheppard, Devon, Lea, Susan M., Handford, Penny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415683/
https://www.ncbi.nlm.nih.gov/pubmed/22326375
http://dx.doi.org/10.1016/j.semcdb.2012.01.009