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Monitoring imatinib plasma concentrations in chronic myeloid leukemia

Imatinib has proved to be effective in the treatment of chronic myeloid leukemia, but plasma levels above 1,000 ng/mL must be achieved to optimize activity. Therapeutic drug monitoring of imatinib is useful for patients that do not present clinical response. There are several analytical methods to m...

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Detalles Bibliográficos
Autores principales: Martins, Darlize Hübner, Wagner, Sandrine Comparsi, dos Santos, Tamyris Vianna, Lizot, Lilian de Lima Feltraco, Antunes, Marina Venzon, Capra, Marcelo, Linden, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415771/
https://www.ncbi.nlm.nih.gov/pubmed/23049322
http://dx.doi.org/10.5581/1516-8484.20110081