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The coevolution of toxin and antitoxin genes drives the dynamics of bacterial addiction complexes and intragenomic conflict

Bacterial genomes commonly contain ‘addiction’ gene complexes that code for both a toxin and a corresponding antitoxin. As long as both genes are expressed, cells carrying the complex can remain healthy. However, loss of the complex (including segregational loss in daughter cells) can entail death o...

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Detalles Bibliográficos
Autores principales: Rankin, Daniel J., Turner, Leighton A., Heinemann, Jack A., Brown, Sam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415908/
https://www.ncbi.nlm.nih.gov/pubmed/22787022
http://dx.doi.org/10.1098/rspb.2012.0942