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SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein

Both human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) encode a unique set of accessory proteins that enhance viral replication in the host. Two similar accessory proteins, Vpx and Vpr, are encoded by HIV-2. In contrast, HIV-1 encodes Vpr but not Vpx. Recent studies have ind...

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Detalles Bibliográficos
Autores principales: Fujita, Mikako, Nomaguchi, Masako, Adachi, Akio, Otsuka, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415948/
https://www.ncbi.nlm.nih.gov/pubmed/22908011
http://dx.doi.org/10.3389/fmicb.2012.00297