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Ectopic ERK expression induces phenotypic conversion of C10 cells and alters DNA methyltransferase expression
BACKGROUND: Many lung carcinogens activate mitogen activated protein kinase (MAPK) pathways and DNA methyltransferases (DNMTs) are under investigation as therapeutic targets for lung cancer. Our goal is to determine whether C10 type II alveolar epithelial cells are a sensitive model to investigate E...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416577/ https://www.ncbi.nlm.nih.gov/pubmed/22559742 http://dx.doi.org/10.1186/1756-0500-5-217 |