Severe diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice

BACKGROUND: Type-2 Diabetes is a major health concern in the United States and other Westernized countries, with prevalence increasing yearly. There is a need to better model and predict adverse drug reactions, drug-induced liver injury, and drug efficacy in this population. Because transporters sig...

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Detalles Bibliográficos
Autores principales: More, Vijay R, Wen, Xia, Thomas, Paul E, Aleksunes, Lauren M, Slitt, Angela L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416584/
https://www.ncbi.nlm.nih.gov/pubmed/22524730
http://dx.doi.org/10.1186/1476-5926-11-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416584/
https://www.ncbi.nlm.nih.gov/pubmed/22524730
http://dx.doi.org/10.1186/1476-5926-11-1

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