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Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae

BACKGROUND: Secretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the endoplasmic reticulum membrane. After passing through the secretory pathway, most proteins are secreted to the environment. Here, we describe the modification of an expression v...

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Detalles Bibliográficos
Autores principales: Klatt, Stephan, Konthur, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416730/
https://www.ncbi.nlm.nih.gov/pubmed/22830363
http://dx.doi.org/10.1186/1475-2859-11-97