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Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae
BACKGROUND: Secretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the endoplasmic reticulum membrane. After passing through the secretory pathway, most proteins are secreted to the environment. Here, we describe the modification of an expression v...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416730/ https://www.ncbi.nlm.nih.gov/pubmed/22830363 http://dx.doi.org/10.1186/1475-2859-11-97 |