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Hallmarks of human “immunosenescence”: adaptation or dysregulation?
Is immunosenescence an intrinsic ageing process leading to dysregulation of immunity or an adaptive response of the individual to pathogen exposure? Age-associated differences in bone marrow immune cell output and thymic involution suggest the former. Accepted hallmarks of immunosenescence (decrease...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416738/ https://www.ncbi.nlm.nih.gov/pubmed/22830639 http://dx.doi.org/10.1186/1742-4933-9-15 |