Pertussis Toxin, an Inhibitor of G(αi) PCR, Inhibits Bile Acid- and Cytokine-Induced Apoptosis in Primary Rat Hepatocytes

Excessive hepatocyte apoptosis is a common event in acute and chronic liver diseases leading to loss of functional liver tissue. Approaches to prevent apoptosis have therefore high potential for the treatment of liver disease. G-protein coupled receptors (GPCR) play crucial roles in cell fate (proli...

Descripción completa

Detalles Bibliográficos
Autores principales: Karimian, Golnar, Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416748/
https://www.ncbi.nlm.nih.gov/pubmed/22900098
http://dx.doi.org/10.1371/journal.pone.0043156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416748/
https://www.ncbi.nlm.nih.gov/pubmed/22900098
http://dx.doi.org/10.1371/journal.pone.0043156

Ejemplares similares