The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins

Raine syndrome is caused by mutations in FAM20C, which had been reported to encode a secreted component of bone and teeth. We found that FAM20C encodes a Golgi-localized protein kinase, distantly related to the Golgi-localized kinase Four-jointed. Drosophila also encode a Golgi-localized protein kin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishikawa, Hiroyuki O., Xu, Aiguo, Ogura, Eri, Manning, Gerard, Irvine, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416761/
https://www.ncbi.nlm.nih.gov/pubmed/22900076
http://dx.doi.org/10.1371/journal.pone.0042988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416761/
https://www.ncbi.nlm.nih.gov/pubmed/22900076
http://dx.doi.org/10.1371/journal.pone.0042988

Ejemplares similares