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The Raine Syndrome Protein FAM20C Is a Golgi Kinase That Phosphorylates Bio-Mineralization Proteins
Raine syndrome is caused by mutations in FAM20C, which had been reported to encode a secreted component of bone and teeth. We found that FAM20C encodes a Golgi-localized protein kinase, distantly related to the Golgi-localized kinase Four-jointed. Drosophila also encode a Golgi-localized protein kin...
Autores principales: | Ishikawa, Hiroyuki O., Xu, Aiguo, Ogura, Eri, Manning, Gerard, Irvine, Kenneth D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416761/ https://www.ncbi.nlm.nih.gov/pubmed/22900076 http://dx.doi.org/10.1371/journal.pone.0042988 |
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