Conditional Knockout of the Menkes Disease Copper Transporter Demonstrates Its Critical Role in Embryogenesis

The transition metal, copper (Cu), is an enzymatic cofactor required for a wide range of biochemical processes. Its essentiality is demonstrated by Menkes disease, an X-linked copper deficiency disorder characterized by defects in nervous-, cardiovascular- and skeletal systems, and is caused by muta...

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Detalles Bibliográficos
Autores principales: Wang, Yanfang, Zhu, Sha, Weisman, Gary A., Gitlin, Jonathan D., Petris, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416770/
https://www.ncbi.nlm.nih.gov/pubmed/22900086
http://dx.doi.org/10.1371/journal.pone.0043039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416770/
https://www.ncbi.nlm.nih.gov/pubmed/22900086
http://dx.doi.org/10.1371/journal.pone.0043039

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