Sensitivity to TOP2 Targeting Chemotherapeutics Is Regulated by Oct1 and FILIP1L

Topoisomerase II (TOP2) targeting drugs like doxorubicin and etoposide are frontline chemotherapeutics for a wide variety of solid and hematological malignancies, including breast and ovarian adenocarcinomas, lung cancers, soft tissue sarcomas, leukemias and lymphomas. These agents cause a block in...

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Detalles Bibliográficos
Autores principales: Lu, Huarui, Hallstrom, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416772/
https://www.ncbi.nlm.nih.gov/pubmed/22900064
http://dx.doi.org/10.1371/journal.pone.0042921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416772/
https://www.ncbi.nlm.nih.gov/pubmed/22900064
http://dx.doi.org/10.1371/journal.pone.0042921

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