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Blockage of Heme Oxygenase-1 Abrogates the Protective Effect of Regulatory T Cells on Murine Pregnancy and Promotes the Maturation of Dendritic Cells

Regulatory T cells (Treg) play an important role in fetal protection. They expand during normal pregnancy and protect fetal antigens from maternal effector cells. Their effect is associated with the up-regulation of tolerance-associated molecules at the fetal-maternal interface. Among these, Heme Ox...

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Detalles Bibliográficos
Autores principales: Schumacher, Anne, Wafula, Paul Ojiambo, Teles, Ana, El-Mousleh, Tarek, Linzke, Nadja, Zenclussen, Maria Laura, Langwisch, Stefanie, Heinze, Kristina, Wollenberg, Ivonne, Casalis, Pablo Ariel, Volk, Hans-Dieter, Fest, Stefan, Zenclussen, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416808/
https://www.ncbi.nlm.nih.gov/pubmed/22900010
http://dx.doi.org/10.1371/journal.pone.0042301