A Single Protofilament Is Sufficient to Support Unidirectional Walking of Dynein and Kinesin

Cytoplasmic dynein and kinesin are two-headed microtubule motor proteins that move in opposite directions on microtubules. It is known that kinesin steps by a ‘hand-over-hand’ mechanism, but it is unclear by which mechanism dynein steps. Because dynein has a completely different structure from that...

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Detalles Bibliográficos
Autores principales: Shibata, Keitaro, Miura, Michi, Watanabe, Yuta, Saito, Kei, Nishimura, Atsuko, Furuta, Ken'ya, Toyoshima, Yoko Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416812/
https://www.ncbi.nlm.nih.gov/pubmed/22900078
http://dx.doi.org/10.1371/journal.pone.0042990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416812/
https://www.ncbi.nlm.nih.gov/pubmed/22900078
http://dx.doi.org/10.1371/journal.pone.0042990

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