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Antibodies to MHC Class II Molecules Induce Autoimmunity: Critical Role for Macrophages in the Immunopathogenesis of Obliterative Airway Disease

Previous studies have shown that intrabronchial administration of antibodies (Abs) to MHC class I resulted in development of obliterative airway disease (OAD), a correlate of chronic human lung allograft rejection. Since development of Abs specific to mismatched donor HLA class II have also been ass...

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Detalles Bibliográficos
Autores principales: Takenaka, Masashi, Tiriveedhi, Venkataswarup, Subramanian, Vijay, Hoshinaga, Kiyotaka, Patterson, Alexander G., Mohanakumar, Thalachallour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416847/
https://www.ncbi.nlm.nih.gov/pubmed/22900015
http://dx.doi.org/10.1371/journal.pone.0042370