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Not All Sequence Tags Are Created Equal: Designing and Validating Sequence Identification Tags Robust to Indels
Ligating adapters with unique synthetic oligonucleotide sequences (sequence tags) onto individual DNA samples before massively parallel sequencing is a popular and efficient way to obtain sequence data from many individual samples. Tag sequences should be numerous and sufficiently different to ensur...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416851/ https://www.ncbi.nlm.nih.gov/pubmed/22900027 http://dx.doi.org/10.1371/journal.pone.0042543 |