Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice

BACKGROUND: Copy number variation (CNV) at the 15q11.2 region, which includes a gene that codes for CYFIP1 (cytoplasmic FMR1 interacting protein 1), has been implicated in autism, intellectual disability and additional neuropsychiatric phenotypes. In the current study we studied the function of Cyfi...

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Detalles Bibliográficos
Autores principales: Bozdagi, Ozlem, Sakurai, Takeshi, Dorr, Nathan, Pilorge, Marion, Takahashi, Nagahide, Buxbaum, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416859/
https://www.ncbi.nlm.nih.gov/pubmed/22900020
http://dx.doi.org/10.1371/journal.pone.0042422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416859/
https://www.ncbi.nlm.nih.gov/pubmed/22900020
http://dx.doi.org/10.1371/journal.pone.0042422

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