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TC10 Is Regulated by Caveolin in 3T3-L1 Adipocytes

BACKGROUND: TC10 is a small GTPase found in lipid raft microdomains of adipocytes. The protein undergoes activation in response to insulin, and plays a key role in the regulation of glucose uptake by the hormone. METHODOLOGY/PRINCIPAL FINDINGS: TC10 requires high concentrations of magnesium in order...

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Detalles Bibliográficos
Autores principales: Bridges, Dave, Chang, Louise, Lodhi, Irfan J., Clark, Natalie A., Saltiel, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416860/
https://www.ncbi.nlm.nih.gov/pubmed/22900022
http://dx.doi.org/10.1371/journal.pone.0042451