Overexpressed Galectin-3 in Pancreatic Cancer Induces Cell Proliferation and Invasion by Binding Ras and Activating Ras Signaling

Pancreatic cancer (PDAC) is a lethal disease with a five-year survival of 3–5%. Mutations in K-Ras are found in nearly all cases, but K-Ras mutations alone are not sufficient for the development of PDAC. Additional factors contribute to activation of Ras signaling and lead to tumor formation. Galect...

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Detalles Bibliográficos
Autores principales: Song, Shumei, Ji, Baoan, Ramachandran, Vijaya, Wang, Huamin, Hafley, Margarete, Logsdon, Craig, Bresalier, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416861/
https://www.ncbi.nlm.nih.gov/pubmed/22900040
http://dx.doi.org/10.1371/journal.pone.0042699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416861/
https://www.ncbi.nlm.nih.gov/pubmed/22900040
http://dx.doi.org/10.1371/journal.pone.0042699

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