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M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression

OBJECTIVES: Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis. However, the role of M2-polarized macrophages in the growth and metastasis of lung adenocarcinoma remains enigmatic. The aim of this study w...

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Detalles Bibliográficos
Autores principales: Zhang, Bicheng, Zhang, Yafei, Yao, Guoqing, Gao, Juan, Yang, Bo, Zhao, Yong, Rao, Zhiguo, Gao, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416895/
https://www.ncbi.nlm.nih.gov/pubmed/22948457
http://dx.doi.org/10.6061/clinics/2012(08)08